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Chemistry of Heterocyclic Compounds

, Volume 28, Issue 11, pp 1323–1330 | Cite as

Nitroazines 18. Arylation and destruction of 6-nitro-1,2,4-triazolo[1,5-a]pyrimidines

  • V. L. Rusinov
  • M. N. Kushnir
  • O. N. Chupakhin
  • G. G. Aleksandrov
Article

Abstract

6-Ntiro-7-aryl-1,2,4-triazolo[1,5-a]pyrimidines were synthesized by treatment of the corresponding 7-oxo compounds with phosphorus oxychloride in the presence of N,N-dialkylanilines. The 7-(N-methyl-p-methoxyphenylamino) derivatives were formed under the same conditions with N,N-dimethyl-p-anisidine. The nitroarylazolopyrimidines produced underwent destruction to give ω-nitroacetophenones on treatment with water. The influence of substituenis on the course of the reaction is shown and the mechanism is discussed.

Keywords

Phosphorus Organic Chemistry Pyrimidine Oxychloride Phosphorus Oxychloride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • V. L. Rusinov
    • 1
  • M. N. Kushnir
    • 1
  • O. N. Chupakhin
    • 1
  • G. G. Aleksandrov
    • 1
  1. 1.Urals Polytechnical InstituteEkaterinburg

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