Chemistry of Heterocyclic Compounds

, Volume 28, Issue 11, pp 1236–1244 | Cite as

Synthesis of heterocycles based on the products of the addition of polyhalogenoalkanes to unsaturated systems. 3. Structure and stereochemistry of substituted N-furylformamidines

  • D. M. Antonov
  • L. I. Belen'kii
  • V. S. Bogdanov
  • A. A. Dudinov
  • M. M. Krayushin
  • V. N. Nesterov
  • Yu. T. Struchkov
  • B. I. Ugrak


It was established with the aid of the 1H, 13C, and 15N NMR spectra as well as the x-ray structural analysis that the substituted furylformamidines, which are key compounds in the synthesis of furo[2,3-d]pyrimidines, are E-isomers of N(1) -furyl-N(2) -R-formamidines (R=H, Alk, Ar), independently of the nature of the substituent at the second N atom, and occur mainly in the form of the antiplanar rotamers.


Organic Chemistry Structural Analysis Pyrimidine Unsaturated System 
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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • D. M. Antonov
    • 1
  • L. I. Belen'kii
    • 1
  • V. S. Bogdanov
    • 1
  • A. A. Dudinov
    • 1
  • M. M. Krayushin
    • 1
  • V. N. Nesterov
    • 1
  • Yu. T. Struchkov
    • 1
  • B. I. Ugrak
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryRussian Academy of SciencesMoscow

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