Abstract
1-Aryl-2,5,7-trimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidines are formed from the cyclization of N-acetyl-2-arylamino-4,6-dimethylnicotinonitriles by perchloric acid in a mixture of acetic acid and acetic anhydride. 1-Aryl-2-acetonyl-5,7-dimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidines areformedonheating2-arylamino-4,6-dimethylnicotinamides with acetic anhydride. These and analogous compounds were obtained by acylation of 1-aryl-2,5,7-trimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidines with acetic anhydride or benzoyl chloride.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1234–1236, September, 1992.
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Demina, L.M., Konshin, M.E. Synthesis and properties of 1-aryl-2,5,7-trimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidines. Chem Heterocycl Compd 28, 1046–1047 (1992). https://doi.org/10.1007/BF00531484
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DOI: https://doi.org/10.1007/BF00531484