Chemistry of Heterocyclic Compounds

, Volume 28, Issue 12, pp 1439–1444 | Cite as

Reactions of 1,1-dialkylthiosemicarbazides with propiolic acid and its esters

  • V. Ya. Kauss
  • A. F. Mishnev
  • I. Ya. Kalvin'sh


The betaines 2-amino-4,4-dimethyl-δ2-1,3,4-thiadiazolin-4-io-5-acetates are formed in the reaction of 1,1-dimethylthiosemicarbazides with propiolic acid. 2-Amino-4,4-disubstituted-5-carboalkoxy-methyl-δ2-1,3,4-thiadiazolinium chlorides, the structure of which has been confirmed by X-ray crystallography, are formed by the reaction of 1,1-disubstituted thiosemicarbazides lower alkyl propiolates in the presence of hydrochloric acid.


Chloride Ester Organic Chemistry Hydrochloric Acid Betaine 
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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • V. Ya. Kauss
    • 1
  • A. F. Mishnev
    • 1
  • I. Ya. Kalvin'sh
    • 1
  1. 1.Latvian Institute of Organic ChemistryRigaLatvia

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