Abstract
It has been shown that the alkylation of 2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one takes place at the oxygen atom, but electrophilic substitution takes place mainly at position 8 of the molecule (the ortho position relative to the hydroxy group).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1660–1666, December, 1992.
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Smirnov, L.D., Nikitin, S.V., Chernyshev, A.I. et al. Structure and reactivity of 2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one. Chem Heterocycl Compd 28, 1425–1431 (1992). https://doi.org/10.1007/BF00531298
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DOI: https://doi.org/10.1007/BF00531298