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Chemistry of Heterocyclic Compounds

, Volume 28, Issue 12, pp 1420–1424 | Cite as

Conversions of methyl esters of (6-methyl-2-methylthio-4-pyrimidinyloxy)- and (3,4-dihydro-6-methyl-2-methylthio-4-oxo-3-pyrimidinyl)acetic acids

  • P. Vainilavichyus
  • V. Syadyaryavichyute
  • S. Motsishkite
Article
  • 39 Downloads

Abstract

A study has been made of nucleophilic reactions (hydrolysis, hydrazinolysis, ammonolysis, reduction) and electrophilic reactions (bromination, nitration) of isomeric methyl esters of (6-methyl-2-methylthio-4-pyrimidinyloxy) acetic acid and (3,4-dihydro-6-methyl-2-methylthio-4-oxo-3-pyrimidinyl)acetic acid. Carboxyl-group derivatives and also derivatives with substituents in position 5 of the pyrimidine ring have been synthesized.

Keywords

Methyl Acetic Ester Hydrolysis Acetic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    P. I. Vainilavichyus and V. Yu. Syadyaryavichyute, Khim. Geterotsikl. Soedin., No. 12, 1655 (1987).Google Scholar
  2. 2.
    D. J. Brown, in: The Pyrimidines, Supplement I, edited by A. Weisberger and E. C. Taylor, Wiley-Interscience, New York (1970), p. 305.Google Scholar
  3. 3.
    P. I. Vainilavichyus, M.-M. V. Burbulene, V.-S. M. Rochka, N.-D. I. Lautsyuvene, and G. P. Polukordas, USSR Inventor's Certificate 791,746, Byull. Izobret., No. 48 (1980).Google Scholar
  4. 4.
    P. I. Vainilavichyus, M.-M. V. Burbulene, V.-S. M. Rochka, and N.-D. I. Lautsyuvene, Khim.-Farm. Zh., No. 8, 35 (1982).Google Scholar
  5. 5.
    Ya. A. Levin, N. A. Gul'kina, and V. A. Kukhtin, Zh. Obshch. Khim., 33, 2673 (1963).Google Scholar
  6. 6.
    E. Peters, H. J. Minnemeyer, A. W. Spears, and H. Tieckelmann, J. Org. Chem., 25, 2137 (1960).Google Scholar
  7. 7.
    P. I. Vainilavichyus and V. Yu. Syadyaryavichyute, Khim. Geterotsikl. Soedin., No. 11, 1520 (1987).Google Scholar

Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • P. Vainilavichyus
    • 1
  • V. Syadyaryavichyute
    • 1
  • S. Motsishkite
    • 1
  1. 1.Vilnius UniversityVilnius

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