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Chemistry of Heterocyclic Compounds

, Volume 28, Issue 12, pp 1379–1381 | Cite as

Synthesis and properties of 2-(2-oxoindolin-3-ylidene)-2-cyanoacetic acid piperidides and morpholides

  • S. V. Ukhov
  • M. E. Konshin
Article
  • 36 Downloads

Abstract

The reaction of isatins with cyanoacetic acid piperidide or morpholide gives the corresponding derivatives of 2-(2-oxoindolin-3-ylidene)-2-cyanoacetic acid, which may be reduced to give amides of 2-(2-oxoindolin-3-yl)-2-cyanoacetic acid and react with ethanolic alkali to give quinoline derivatives.

Keywords

Organic Chemistry Amide Quinoline Isatin Quinoline Derivative 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    J. Harley-Mason and R. Inleby, J. Chem. Soc., 3639 (1958).Google Scholar
  2. 2.
    A. M. Fahmy and M. Z. A. Badr, J. Heterocycl. Chem., 21, No. 4, 1233 (1984).Google Scholar

Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • S. V. Ukhov
    • 1
  • M. E. Konshin
    • 1
  1. 1.Perm Pharmaceutical InstitutePerm

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