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Synthesis of 3,4-dihydroisoxazoles — Derivatives of ω-carbonyl-substituted 1,3,3-trimethyl-2-methyleneindolines and their chemical reactions

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Stable spiro compounds containing a dihydroisoxazole ring are formed by the reaction of ω-carbonyl-substituted 2-methyleneindolines with hydroxylamine. These compounds are converted in acid media into isoxazoles with scission of the indoline unit.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ukrainian Academy of Sciences, 252660, Kiev

    A. A. Tolmachev, L. N. Babichenko & A. K. Sheinkman

  2. Dnepropetrovsk Structural Engineering Institute, 320092, Dnepropetrovsk

    A. A. Tolmachev, L. N. Babichenko & A. K. Sheinkman

Authors
  1. A. A. Tolmachev
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  2. L. N. Babichenko
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  3. A. K. Sheinkman
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, 523–528, April, 1993.

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Tolmachev, A.A., Babichenko, L.N. & Sheinkman, A.K. Synthesis of 3,4-dihydroisoxazoles — Derivatives of ω-carbonyl-substituted 1,3,3-trimethyl-2-methyleneindolines and their chemical reactions. Chem Heterocycl Compd 29, 446–451 (1993). https://doi.org/10.1007/BF00529885

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  • DOI: https://doi.org/10.1007/BF00529885

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