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Three component condensation of 3-amino-1,2,4-triazole with carbonyl compounds. A new synthesis of 1,2,4-triazolo[1,5-a]pyrimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Three component condensation of 3-amino-1,2,4-triazole with an aromatic aldehyde and ketone gives 1,2,4-triazolo[1,5-a]-pyrimidines. An x-ray structural investigation of 5-phenyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]benzo[h]quinazoline was undertaken in order to determine the course of this reaction.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 481–485, April, 1993.

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Desenko, S.M., Orlov, V.D., Getmanskii, N.V. et al. Three component condensation of 3-amino-1,2,4-triazole with carbonyl compounds. A new synthesis of 1,2,4-triazolo[1,5-a]pyrimidines. Chem Heterocycl Compd 29, 406–410 (1993). https://doi.org/10.1007/BF00529878

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  • DOI: https://doi.org/10.1007/BF00529878

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