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Reaction of 2-thiouracil with carboxylic acid 1,2,2,2-tetrachloroethylamides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Amidoalkylation of 2-thiouracil with 1,2,2,2-tetrachloroethylamides in the presence of triethylamine or sodium hydroxide gives products of S-, O-, and N-substitution, depending on the reaction conditions.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petroleum Chemistry, Ukrainian Academy of Sciences, 253160, Kiev

    S. V. Klyuchko, B. M. Khutova, A. B. Rozhenko, E. A. Romanenko, S. I. Vdovenko, L. I. Rybchenko, L. P. Prikazchikova & B. S. Drach

Authors
  1. S. V. Klyuchko
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  2. B. M. Khutova
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  3. A. B. Rozhenko
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  4. E. A. Romanenko
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  5. S. I. Vdovenko
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  6. L. I. Rybchenko
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  7. L. P. Prikazchikova
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  8. B. S. Drach
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 95–100, January, 1992.

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Klyuchko, S.V., Khutova, B.M., Rozhenko, A.B. et al. Reaction of 2-thiouracil with carboxylic acid 1,2,2,2-tetrachloroethylamides. Chem Heterocycl Compd 28, 83–87 (1992). https://doi.org/10.1007/BF00529487

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  • DOI: https://doi.org/10.1007/BF00529487

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