Advertisement

Chemistry of Heterocyclic Compounds

, Volume 28, Issue 3, pp 327–330 | Cite as

Functionalization of the ω-chain of prostanoids by the selective opening of the heterocycle in 3-isoxazolylcyclopentanone derivatives

  • F. A. Lakhvich
  • E. V. Koroleva
  • T. V. Chernikhova
Article

Abstract

The reaction of reducing agents with functionalized isoxazole derivatives has been studied; 13-amino-15-ketoprostanoids have been synthesized.

Keywords

Organic Chemistry Isoxazole Selective Opening Isoxazole Derivative 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    F. A. Lakhvich, E. V. Koroleva, and A. A. Akhrem, Khim. Geterotsikl. Soedin., No. 4, 435 (1989).Google Scholar
  2. 2.
    F. A. Lakhvich, T. V. Yankova, E. V. Koroleva, L. G. Lis, and A. A. Akhrem, Zh. Org. Khim., 24, 1665 (1988).Google Scholar
  3. 3.
    F. A. Lakhvich, E. V. Koroleva, I. L. Rubinova, and T. V. Yankova, Izv. Akad. Nauk BSSR, Ser. Khim., No. 4, 66 (1987).Google Scholar
  4. 4.
    A. A. Akhrem, F. A. Lakhvich, and V. A. Khripach, Khim. Geterotsikl. Soedin., No. 9, 1156 (1981).Google Scholar
  5. 5.
    A. A. Akhrem, F. A. Lakhvich, V. A. Khripach, and I. B. Klebanovich, Dokl. Akad. Nauk SSSR, 244, 615 (1979).Google Scholar
  6. 6.
    A. P. Kozikowski and M. Adamczyk, Tetrahedron Lett., 23, 3123 (1982).Google Scholar
  7. 7.
    E. V. Koroleva, F. A. Lakhvich, and T. V. Yankova, Khim. Geterotsikl. Soedin., No. 11. 1576 (1987).Google Scholar
  8. 8.
    A. A. Akhrem and E. V. Koroleva, Izv. Akad. Nauk BSSR, Ser. Khim., No. 6, 103 (1978).Google Scholar
  9. 9.
    G. Lunn, J. Org. Chem., 52, 1043 (1987).Google Scholar
  10. 10.
    M. Nitta and T. Kobayashi, J. Chem. Soc., Perkin 1, No. 7, 1401 (1985).Google Scholar

Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • F. A. Lakhvich
    • 1
  • E. V. Koroleva
    • 1
  • T. V. Chernikhova
    • 1
  1. 1.Institute of Bioorganic ChemistryBelorussian Academy of SciencesMinsk

Personalised recommendations