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Some substitution and heterocyclization reactions based on 1,4-dihydropyridines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Data on the bromination, chlorination, and bromolactonization of 4-aryl-1,4-dihydropyridines are correlated. The reactions of the products of bromination of 4-aryl-1,4-dihydropyridines with various nucleophilic agents (amines and iodide, azide, and thiocyanate ions) and reactions involving the heterocyclization of the products of substitution of the 2,6-methyl groups of 4-aryl-1,4-dihydropyridines, which lead to condensed furo-, difuro-, pyrrolo-, dipyrrolo-, furopyrrolo-, and furothiazolopyridines and thiazolopyridothiadiazines are examined.

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Authors and Affiliations

  1. Institute of Organic Synthesis, Latvian Academy of Sciences, 226006, Riga

    I. P. Skrastin'sh & G. Ya. Dubur

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  1. I. P. Skrastin'sh
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  2. G. Ya. Dubur
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 781–791, June, 1992.

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Skrastin'sh, I.P., Dubur, G.Y. Some substitution and heterocyclization reactions based on 1,4-dihydropyridines. Chem Heterocycl Compd 28, 648–657 (1992). https://doi.org/10.1007/BF00529335

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  • DOI: https://doi.org/10.1007/BF00529335

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