Abstract
A method was developed for the N-alkylation of indole and its derivatives by alkyl halides in the presence of sodium hydroxide and catalytic amounts of trimethylbenzylammonium chloride.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 191–193, February, 1976.
The authors thank Prof. A. N. Kost for his critical remarks and advice during a discussion of the results of our research on the alkylation of N-carbomethoxy-3-indolylcyanoacetic ester
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Suvorov, N.N., Smushkevich, Y.I., Velezheva, V.S. et al. Synthesis of N-substituted indoles by extractive alkylation. Chem Heterocycl Compd 12, 167–169 (1976). https://doi.org/10.1007/BF00523961
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DOI: https://doi.org/10.1007/BF00523961