Abstract
The possibility of the electrophilic substitution of various positions of the 5-hydroxypyrimidine ring in a weakly basic medium is demonstrated in the case of aminomethylation and diazo coupling. It was found that the ortho positions of 5-hydroxypyrimidine are more reactive than the para position with respect to the hydroxy group.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 393–396, March, 1982.
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Gashev, S.B., Smirnov, L.D. Investigation of the electrophilic reactions of 5-hydroxypyrimidine. Chem Heterocycl Compd 18, 297–299 (1982). https://doi.org/10.1007/BF00522134
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DOI: https://doi.org/10.1007/BF00522134