Abstract
The reactions of 4-amino derivatives of imidazo[4.5-c]pyridin-2-ones with α-bromomethylketones have been studied. Depending on the nature of the reagents and the reaction conditions, either 5-acylmethyl salts of the starting amine or 2-substituted imidazo[4.5-c]imidazo[1,2-a]pyridin-8-ones can be obtained. The latter compounds are also easily obtained by treatment of the 5-acylmethyl salts with alkali.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
Yu. M. Yutilov and I. A. Svertilova, Khim. Geterotsikl. Soedin., No. 1, 97 (1986).
Yu. M. Yutilov and I. A. Svertilova, Khim. Geterotsikl. Soedin., No. 1, 138 (1973).
I. A. Svertilova and Yu. M. Yutilov, USSR Inventor's Cert. No. 521,277; Byull. Izobr., No. 26, 80 (1976).
Yu. M. Yutilov, K. M. Khabarov, and I. A. Svertilova, VINITI, No. 4182-79, December 10, 1979.
W. W. Paudler and H. L. Blewitt, J. Org. Chem., 31., 1295 (1966).
W. W. Paudler and H. L. Blewitt, J. Org. Chem., 30, 4081 (1965).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 227–232, February, 1986.
Rights and permissions
About this article
Cite this article
Yutilov, Y.M., Khabarov, K.M. Reaction of 4-aminoimadazo[4.5-c]pyridin-2-ones with α-bromomethylketones. Chem Heterocycl Compd 22, 180–186 (1986). https://doi.org/10.1007/BF00519940
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00519940