Abstract
A review is given of the synthetic analogs of the prostacyclins having greater chemical and metabolic stability than prostacyclin itself. Possible routes for synthesis are discussed.
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This review is an expanded version of the plenary lecture of the authors at the 3rd All-Union Conference on Synthetic and Applied Studies of Prostaglandins [in Russian], Ufa (1984).
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 579–595, May, 1986.
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Freimanis, Y.F., Dikovskaya, K. Analogues of prostacyclin (PGI2) modified in the 2-oxabicyclo[3.3.0]octane fragment (review). Chem Heterocycl Compd 22, 471–485 (1986). https://doi.org/10.1007/BF00519522
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DOI: https://doi.org/10.1007/BF00519522