Chemistry of Heterocyclic Compounds

, Volume 19, Issue 8, pp 868–870 | Cite as

Effect of a tosyl protective group on the direction of the acylation of 2-aminoindole

  • V. V. Men'shikov
  • R. S. Sagitullin


The introduction of a tosyl grouping in the 2-aminoindole molecule substantially changes the direction of the acylation reaction. Not only substitution at the C(3) atom but also transacylation at the amino group with the elimination of the tosyl group are observed in the acylation of 2-tosylamidoindole in the presence of phosphoric acid.


Organic Chemistry Phosphoric Acid Tosyl Protective Group Acylation Reaction 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • V. V. Men'shikov
    • 1
    • 2
  • R. S. Sagitullin
    • 1
    • 2
  1. 1.M. V. Lomonosov Moscow State UniversityMoscow
  2. 2.Omsk State UniversityOmsk

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