Abstract
The introduction of a tosyl grouping in the 2-aminoindole molecule substantially changes the direction of the acylation reaction. Not only substitution at the C(3) atom but also transacylation at the amino group with the elimination of the tosyl group are observed in the acylation of 2-tosylamidoindole in the presence of phosphoric acid.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1082–1085, August, 1983.
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Men'shikov, V.V., Sagitullin, R.S. Effect of a tosyl protective group on the direction of the acylation of 2-aminoindole. Chem Heterocycl Compd 19, 868–870 (1983). https://doi.org/10.1007/BF00516452
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DOI: https://doi.org/10.1007/BF00516452