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Chemistry of Heterocyclic Compounds

, Volume 19, Issue 8, pp 838–841 | Cite as

Ring-chain tautomerism of β-keto ester thiobenzoylhydrazones

  • V. N. Nikolaev
  • S. I. Yakimovich
  • N. V. Koshmina
  • K. N. Zelenin
  • V. V. Alekseev
  • V. A. Khrustalev
Article
  • 30 Downloads

Abstract

The products of condensation of thiobenzhydrazide with methyl acetoacetate and its α-alkyl-substituted homologs have the structure of the corresponding 2,3-dihydro-1,3,4-thiadiazoles; only the derivative of α-isopropylacetoacetic acid ester has the open hydrazone form. The products of the reaction of thiobenzhydrazide with the methyl esters of 2-oxocyclopentane- and 2-oxocyclohexanecarboxylic acid are mixtures of enehydrazine and thiadiazoline forms; the percentage of the latter decreases in polar solvents.

Keywords

Methyl Ester Organic Chemistry Methyl Ester Acid Ester 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • V. N. Nikolaev
    • 1
    • 2
  • S. I. Yakimovich
    • 1
    • 2
  • N. V. Koshmina
    • 1
    • 2
  • K. N. Zelenin
    • 1
    • 2
  • V. V. Alekseev
    • 1
    • 2
  • V. A. Khrustalev
    • 1
    • 2
  1. 1.A. A. Zhdanov Leningrad State UniversityLeningrad
  2. 2.S. M. Kirov Academy of Military MedicineLeningrad

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