Abstract
3-Substituted 2-alkyl-10H-benzo[b]-1,8-naphthyrid-5-ones were obtained by cyclization of 2-anilinonicotinic acids or the corresponding nitriles. The pK2 values of these compounds range from −4.63 to −5.98 and correlate with the σ substituent constants.
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See [1] for Communication 10.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 372–375, March, 1984.
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Shramm, N.I., Konshin, M.E. Research on naphthyridines. 11. Synthesis and ionization constants of substituted 10H-benzo[b]-1,8-naphthyrid-5-ones. Chem Heterocycl Compd 20, 301–304 (1984). https://doi.org/10.1007/BF00515644
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DOI: https://doi.org/10.1007/BF00515644