Abstract
The reaction of arylacetonitriles with the methyl ester of 3-hydroxybenzo[b]thiophene-2-carboxylic acid in the presence of a basic catalyst leads to the previously unreported 2-amino-3-arylbenzo[4,5]thieno[3,2-b]pyran-4-ones. Under the same conditions, the ethyl ester of 4,6-dimethyl-3-hydroxythieno[3,2-c]pyridine-2-carboxylic acid reacts to form derivatives of a new heterocyclic system, pyrano[2′,3′-4,5]-thieno[3,2-c]pyridine.
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Yu. M. Volovenko, V. A. Kitenko, T. V. Shokol, and F. S. Babichev, Dokl. Akad. Nauk Ukr. SSR, Ser. B, No. 7, 42 (1982).
P. Netchitailo, J. Morel, P. Pastor, and B. Decroix, J. Heterocycl. Chem., 15, 337 (1978).
K. Goerlitzer and E. Engler, Arch. Pharm., 313, 385 (1980); Chem. Abstr., 93, 204494 (1980).
P. F. Kador and N. E. Sharpless, Biophys. Chem., 8, 81 (1978); Chem. Abstr., 89, 102621 (1978).
Ya. F. Freimanis, The Chemistry of Enaminoketones, Enaminoimines, and Enanminothiones [in Russian], Izd. Zinatne, Riga (1974), p. 222.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1476–1478, November, 1983.
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Volovenko, Y.M., Litenko, V.A., Khrapak, T.V. et al. The annelation of the 2-aminopyran-4-one ring to condensed thiophenes. Chem Heterocycl Compd 19, 1167–1169 (1983). https://doi.org/10.1007/BF00515348
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DOI: https://doi.org/10.1007/BF00515348