Abstract
Individual diastereomers of aziridine-2-carboxylic acid esters that contain R- and S-valine and R- and S-hexafluorovaline fragments were isolated by high-performance liquid chromatogrpahy (HPLC). The absolute configurations of both asymmetric centers of the diastereomeric esters were determined on the basis of the parameters of the PMR spectra (ΔυAB) and circular dichroism (the sign of the cotton effect at 200–220 nm).
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O. G. Nabiev, M. A. Shakhgel'diev, I. I. Chervin, and R. G. Kostyanovskii, Dokl. Akad. Nauk SSSR, 284, 872 (1985).
A. V. Eremeev, F. D. Polyak, A. F. Mishnev, Ya. Ya. Bleidelis, É. É. Liepin'sh, Sh. S. Nasibov, I. I. Chervin, and R. G. Kostyanovskii, Khim. Geterotsikl. Soedin., No. 11, 1495 (1982).
J. P. Jennings, W. Klyne, and P. M. Scopes, J. Chem. Soc., No. 12, 7211 (1965).
K. Nakajima, F. Takai, T. Tanaka, and K. Okawa, Bull. Chem. Soc. Jpn., 51, 1577 (1978).
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Communication 44 from the series “Asymmetric unbridged nitrogen.” See [1] for communication 43.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1355–1358, October, 1985.
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Solodin, I.V., Polyak, F.D., Eremeev, A.V. et al. Synthesis and absolute configurations of diastereomeric aziridine-2-carboxylic acid derivatives containing valine and hexafluorovaline fragments. Chem Heterocycl Compd 21, 1110–1113 (1985). https://doi.org/10.1007/BF00515248
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DOI: https://doi.org/10.1007/BF00515248