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Chemistry of Heterocyclic Compounds

, Volume 20, Issue 4, pp 409–412 | Cite as

Composition of the products and kinetics of the isopropylation of 1,2,3,4-tetrahydroquinoline in sulfuric acid

  • Z. A. Okhrimenko
  • V. G. Chekhuta
  • O. I. Kachurin
Article
  • 32 Downloads

Abstract

The kinetics of the alkylation of 1,2,3,4-tetrahydroquinoline with isopropyl alcohol in 90% sulfuric acid at 60 °C were studied. It was established that the rate of alkylation in the 5 position is higher than for the corresponding position in the acyclic analog N,2-dimethylaniline; this was ascribed to the Mills—Nixon dynamic effect.

Keywords

Alcohol Organic Chemistry Sulfuric Acid Isopropyl Alcohol Alkylation 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Z. A. Okhrimenko
    • 1
  • V. G. Chekhuta
    • 1
  • O. I. Kachurin
    • 1
  1. 1.Institute of Physical Organic Chemistry and Coal ChemistryAcademy of Sciences of the Ukrainian SSRDonetsk

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