Investigation of the mass-spectrometric behavior of aminomethyl and aminomethylene derivatives of tetrahydrofuran
- 27 Downloads
The principal pathway in the mass-spectrometric fragmentation of aminomethyl-tetrahydrofurans is cleavage of the α-C-C bond, in which a tetrahydrofuranyl radi cal is eliminated in the form of a neutral fragment, and the charge is retained on the amino fragment. This process is completely absent in methylene derivatives for which one of the characteristic fragmentation pathways is cleavage of the β bond with retention of the charge on the hydrofuran fragment. The established mass-spectrometric principles makes it possible to reliably distinguish amino-methyl- and aminomethylenetetrahydrofurans.
KeywordsMethylene Organic Chemistry Tetrahydrofuran Fragmentation Pathway Methylene Derivative
Unable to display preview. Download preview PDF.
- 1.R. A. Karakhanov, M. M. Vartanyan, A. V. Ignatenko, and R. B. Apandiev, Izv. Akad. Nauk SSSR, Ser. Khim., No. 8, 1952 (1980).Google Scholar
- 2.R. A. Karakhanov, M. M. Vartanyan, R. B. Apandiev, and A. V. Ignatenko, Zh. Org. Khim., 18, 226 (1982).Google Scholar
- 3.P. B. Terent'ev, Mass Spectrometry in Organic Chemistry [in Russian], Vysshaya Shkola, Moscow (1979), p. 75.Google Scholar
- 4.D. P. Stevenson, Discuss. Faraday Soc., 10, 35 (1951).Google Scholar
- 5.H. Budzikiewicz, C. Djerassi, and D. Williams, Interpretation of the Mass Spectra of Organic Compounds, Holden-Day, San Francisco (1964).Google Scholar