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Carbolines. 14. Synthesis of 5-azaellipticine

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3-Acetyl-4-methylaminopyridine was obtained by cyanation of 3-acetylpyridine ethyleneketal N-oxide and subsequent chemical transformations of the nitrile group. Condensation of this product with oxindole led to the synthesis of 5H-5,11-dimethylindolo [3,2-j]-1,4-naphthyridine — the aza analog of the alkaloid ellipticine.

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Authors and Affiliations

  1. Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, 664033, Irkutsk

    V. V. Kononova & A. A. Semenov

Authors
  1. V. V. Kononova
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  2. A. A. Semenov
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Additional information

See [1] for communication 13.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1211–1214, September, 1982.

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Kononova, V.V., Semenov, A.A. Carbolines. 14. Synthesis of 5-azaellipticine. Chem Heterocycl Compd 18, 929–932 (1982). https://doi.org/10.1007/BF00513434

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  • DOI: https://doi.org/10.1007/BF00513434

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