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Catalytic reductive dehalogenation of thiophene derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A method for the preparation of 3-substituted derivatives of thiophene by reductive dehalogenation of 2,5-dihalo-substituted thiophenes in the presence of a palladium complex is proposed. The dehalogenation reaction is a stepwise process. The presence of an acyl group in the 3 position increases the rate of the process.

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Authors and Affiliations

  1. N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, 117913, Moscow

    V. Z. Sharf, S. Z. Taits, A. S. Gurovets, Yu. B. Vol'kenshtein, B. P. Fabrichnyi & S. I. Shcherbakova

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  1. V. Z. Sharf
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  2. S. Z. Taits
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  3. A. S. Gurovets
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  4. Yu. B. Vol'kenshtein
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  5. B. P. Fabrichnyi
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  6. S. I. Shcherbakova
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 171–175, February, 1982.

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Sharf, V.Z., Taits, S.Z., Gurovets, A.S. et al. Catalytic reductive dehalogenation of thiophene derivatives. Chem Heterocycl Compd 18, 130–133 (1982). https://doi.org/10.1007/BF00512953

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  • DOI: https://doi.org/10.1007/BF00512953

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