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Investigation of the recyclization of quaternary salts of papaverine and its structural analogs

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The rearrangement of salts of the alkaloid papaverine and its structural analogs under the influence of nucleophilic agents was studied. It is shown that when an alcohol solution of an alkylamine is used as the reagent, replacement of the methoxy group in the 6 position of the isoquinoline ring by an alkylamino group takes place simultaneously with the rearrangement. Rearrangement with retention of the methoxy group can be carried out under the influence of an alkylammonium acetate.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, 117234, Moscow

    V. I. Terenin, L. G. Yudin, R. S. Sagitullin, V. N. Torocheshnikov, V. I. Dulenko, Yu. A. Nikolyukin & A. N. Kost

Authors
  1. V. I. Terenin
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  2. L. G. Yudin
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  3. R. S. Sagitullin
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  4. V. N. Torocheshnikov
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  5. V. I. Dulenko
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  6. Yu. A. Nikolyukin
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  7. A. N. Kost
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Additional information

See [1] for our preliminary communication.

Deceased.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 73–78, January, 1983.

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Terenin, V.I., Yudin, L.G., Sagitullin, R.S. et al. Investigation of the recyclization of quaternary salts of papaverine and its structural analogs. Chem Heterocycl Compd 19, 66–71 (1983). https://doi.org/10.1007/BF00512818

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  • DOI: https://doi.org/10.1007/BF00512818

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