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Formylation of 2-phenyl- and 3-phenyl-5-hydroxybenzofuran derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The Vilsmeier formylation of 2-phenyl- and 3-phenyl-5-hydroxybenzofuran derivatives was studied. It is shown that 2-phenyl-5-methoxybenzofuran is formylated in the 4 position, whereas 3-phenyl-5-methoxybenzofuran is formylated in the 2 position.

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Literature cited

  1. A. N. Grinev, S. A. Zotova, and T. F. Vlasova, Khim. Geterotsikl. Soedin., No. 3, 311 (1976).

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  2. G. Domschke, J. Prakt. Chem., 32, 144 (1966).

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Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow

    A. N. Grinev & S. A. Zotova

Authors
  1. A. N. Grinev
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  2. S. A. Zotova
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1023–1024, August, 1976.

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Grinev, A.N., Zotova, S.A. Formylation of 2-phenyl- and 3-phenyl-5-hydroxybenzofuran derivatives. Chem Heterocycl Compd 12, 845–847 (1976). https://doi.org/10.1007/BF00510096

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  • DOI: https://doi.org/10.1007/BF00510096

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