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Indoles

XXVI. Ratio of indole isomers formed during the fischer cyclization of meta-substituted diethyl ketone phenylhydrazones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

cyclization of m-RC6H4NHN=C (C2H5)2 (R = C2H5, OCH3, Cl) under various conditions always gives a mixture of 4-R-3-methyl-2-ethylindole and 6-R-3-methyl-2-ethylindole isomers with predominance of the latter. The ratios of the isomers formed depend on the catalyst used.

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Literature cited

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Authors and Affiliations

  1. K. A. Timiryazev Moscow Agricultural Institute, USSR

    I. I. Grandberg, L. D. Belyaeva & L. B. Dmitriev

Authors
  1. I. I. Grandberg
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  2. L. D. Belyaeva
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  3. L. B. Dmitriev
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Additional information

See [1] for communication XXV.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1204–1208, September, 1971.

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Grandberg, I.I., Belyaeva, L.D. & Dmitriev, L.B. Indoles. Chem Heterocycl Compd 7, 1131–1134 (1971). https://doi.org/10.1007/BF00510019

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  • DOI: https://doi.org/10.1007/BF00510019

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