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Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1261–1266 | Cite as

Acetals of lactams and acid amides

XXVII. New synthesis of pyrido[2,3-d]pyrimidine derivatives
  • V. G. Granik
  • N. B. Marchenko
  • R. G. Glushkov
Article

Abstract

7-Dimethylamino-5-hydroxypyrido[2,3-d]pyrimidine and pyrrolo-, pyrido, and azepino [2,3-b]pyrido[2,3-d]pyrimidine derivatives were synthesized by reaction of acetals of amides and lactams with 4-amino-5-carbethoxypyrimidine derivatives and subsequent intramolecular cyclization of the intermediate amidines. The reactions of these compounds with phosphorus oxychloride and their alkylation reactions were studied.

Keywords

Acetal Phosphorus Organic Chemistry Amide Pyrimidine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • V. G. Granik
    • 1
  • N. B. Marchenko
    • 1
  • R. G. Glushkov
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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