Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1249–1252 | Cite as

Research on unsaturated azole derivatives

IX. Transformations of 2-ethylnylbenzimidazoles in reactions with aliphatic ketones
  • I. I. Popov
  • A. A. Zubenko
  • A. M. Simonov


The reaction of 1-methyl-5-R-2-ethynylbenzimidazoles with aliphatic ketones leads to either 4-(1-methyl-5-R-2-benzimidazolyl)methylene-1,3-dioxolanes (ether, KOH, 5°C; or NH3, Na, excess ketone) or to alkynylcarbinols (ether, KOH, −5°C, 1 mole of ketone). In contrast to 2-ethynylbenzimidazoles, 1-methyl-3-ethynylindazole is readily hydrated and does not form 1,3-dioxolanes.


Ether Hydrate Organic Chemistry Ketone Azole 
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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • I. I. Popov
    • 1
  • A. A. Zubenko
    • 1
  • A. M. Simonov
    • 1
  1. 1.Rostov State UniversityRostov-on-Don

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