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Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1249–1252 | Cite as

Research on unsaturated azole derivatives

IX. Transformations of 2-ethylnylbenzimidazoles in reactions with aliphatic ketones
  • I. I. Popov
  • A. A. Zubenko
  • A. M. Simonov
Article
  • 33 Downloads

Abstract

The reaction of 1-methyl-5-R-2-ethynylbenzimidazoles with aliphatic ketones leads to either 4-(1-methyl-5-R-2-benzimidazolyl)methylene-1,3-dioxolanes (ether, KOH, 5°C; or NH3, Na, excess ketone) or to alkynylcarbinols (ether, KOH, −5°C, 1 mole of ketone). In contrast to 2-ethynylbenzimidazoles, 1-methyl-3-ethynylindazole is readily hydrated and does not form 1,3-dioxolanes.

Keywords

Ether Hydrate Organic Chemistry Ketone Azole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • I. I. Popov
    • 1
  • A. A. Zubenko
    • 1
  • A. M. Simonov
    • 1
  1. 1.Rostov State UniversityRostov-on-Don

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