Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1241–1245 | Cite as

Reaction of α-chloro-α-isonitrosoacetone with aminopyridines

  • I. N. Azerbaev
  • I. A. Poplavskaya
  • R. G. Kurmangalieva
  • S. F. Khalilova


2-Amino, 2-amino-3-methyl-, and 4-aminopyridine react with α-chloro-α-isonitrosoacetone at the heteroring nitrogen atom to give salts, which are converted to imidazo[1,2-a] pyridines or, in the case of 4-aminopyridine, to 1-(1-oximino-2-oxopropyl)-4-pyridoneimine when they are treated with alkali. Acetylpyridylurea was obtained from chloroisonitrosoacetone and 2-aminopyridine in pyridine.


Nitrogen Organic Chemistry Pyridine Nitrogen Atom 
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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • I. N. Azerbaev
    • 1
  • I. A. Poplavskaya
    • 1
  • R. G. Kurmangalieva
    • 1
  • S. F. Khalilova
    • 1
  1. 1.Institute of Chemical SciencesAcademy of Sciences of the Kazakh SSRAlma-Ata

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