Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1217–1223 | Cite as

Indole derivatives

CXVII. Reaction of 3-aminoindoles with carbon disulfide. Convenient one-step synthesis of 3-indolyl isothiocyanates and indolo[2,3-d]-1,3-thiazines
  • V. S. Velezheva
  • A. V. Yarosh
  • T. A. Kozik
  • N. N. Suvorov


A new one-step method was developed for the preparation of 3-indolyl isothiocyanates by reaction of 3-aminoindoles with carbon disulfide in the presence of sodium ethoxide. It is shown that indolo[2,3-d]-1,3-thiazines are obtained from 3-aminoindoles and carbon disulfide when extraneous bases are absent. The structures of the compounds are confirmed by data from their IR, UV, PMR, and mass spectra.


Sodium Mass Spectrum Organic Chemistry Disulfide Indole 
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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • V. S. Velezheva
    • 1
  • A. V. Yarosh
    • 1
  • T. A. Kozik
    • 1
  • N. N. Suvorov
    • 1
  1. 1.D. I. Mendeleev Moscow Institute of Chemical TechnologyMoscow

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