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Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1208–1210 | Cite as

Behavior of semicarbazones under the conditions of the Fischer reaction

  • M. F. Marshalkin
  • L. N. Yakhontov
Article
  • 32 Downloads

Abstract

Cyclohexanone semicarbazone and phenylsemicarbazone form 1,2,3,4-tetrahydro- and 1,2,3,4,5,6,7,8-octahydrocarbazoles under the conditions of the Fischer reaction. The reaction proceeds through a cyclohexanone azine intermediate. The product of oxidation of the azine is oxidized by air oxygen to 1,2,3,4-tetrahydrocarbazole. The investigated semicarbazones are stable with respect to the action of sodium ethoxide at up to 300°C.

Keywords

Oxidation Oxygen Sodium Organic Chemistry Cyclohexanone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • M. F. Marshalkin
    • 1
  • L. N. Yakhontov
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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