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Chemistry of Heterocyclic Compounds

, Volume 14, Issue 11, pp 1194–1195 | Cite as

Synthesis of 2-trichloromethyloxazolidin-5-ones by reaction of chloral with N,O-trimethylsilyl derivatives of amino acids

  • Yu. A. Davidovich
  • L. A. Pavlova
  • A. Yu. Volkonskii
  • S. V. Rogozhin
Article

Abstract

The corresponding 2-trichloromethyloxazolidin-5-ones were obtained by reaction of chloral with trimethylsilyl (TMS) derivatives of some amino acids. The corresponding oxazolidin-5-ones could not be obtained by the action of chloral on aspartic and glutamic acids.

Keywords

Organic Chemistry Glutamic Acid Chloral Trimethylsilyl 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literature cited

  1. 1.
    E. Dane, R. Heiss, and H. Schäfer, Angew. Chem., 71, 339 (1959).Google Scholar
  2. 2.
    E. Dane, R. Heiss, and H. Schäfer, West German Patent No. 1079648 (1960); Chem. Abstr., 55, 25784a (1961).Google Scholar
  3. 3.
    F. Micheel and W. Meckstroth, Ber., 92, 1675 (1959).Google Scholar
  4. 4.
    M. Bergmann, H. Ensslein, and L. Zervas, Ber., 58, 1034 (1925).Google Scholar

Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • Yu. A. Davidovich
    • 1
  • L. A. Pavlova
    • 1
  • A. Yu. Volkonskii
    • 1
  • S. V. Rogozhin
    • 1
  1. 1.Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRMoscow

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