Chemistry of Heterocyclic Compounds

, Volume 2, Issue 4, pp 460–464 | Cite as

Synthesis of substituted derivatives of imidazo [5, 1-b] benzimidazole

I. 3-(Pyrid-4′-yl)- and 3-phenyl-4-methy limidazo [5, 1-b]benzimidazoles
  • V. M. Aryuzina
  • M. N. Shchukina


Heating, either molten or in high-boiling solvents, 1-methyl-2-[(N-phenylthiocarbamoyl)amino] (pyrid-4′-yl)-methylbenzimidazole, or refluxing with phosphorus oxychloride in benzene acyl derivatives of 1-methyl-2-[(pyrid-4′-yl)(amino)]- and 1-methyl-2 [(phenyl)(amino)]-methylbenzimidazoles, gives the corresponding derivatives of the imidazo [5, 1-b] benzimidazole system, hitherto undescribed in the literature.


Phosphorus Benzene Organic Chemistry Phenyl Benzimidazole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    W. Ried and F. Grull, Chem. Ber., 96, 130, 1963.Google Scholar
  2. 2.
    V. G. Ermolaeva and M. N. Shchukina, ZhOKh, 32, 2664, 1962.Google Scholar
  3. 3.
    V. V. Avidon and M. N. Shchukina, KhGS [Chemistry of Heterocyclic Compounds], I, 64, 1965.Google Scholar
  4. 4.
    A. F. Pozharskii and A. M. Simonov, ZhOKh, 33, 179, 1963.Google Scholar
  5. 5.
    P. W. Alley and D. A. Shirley, J. Org. Chem., 23, 1791, 1958.Google Scholar
  6. 6.
    British Patent no. 885 520; C. A., 57, P7428, 1962.Google Scholar
  7. 7.
    H. Gilman, J. A. Beel, C. G. Brannen, M. W. Bullock, G. E. Dunn, and L. S. Miller, J. Am. Chem. Soc., 71, 1499, 1949.Google Scholar

Copyright information

© The Faraday Press, Inc. 1967

Authors and Affiliations

  • V. M. Aryuzina
    • 1
  • M. N. Shchukina
    • 1
  1. 1.Ordzhonikidize All-Union Scientific Research Chemical and Pharmaceutical Research InstituteMoscow

Personalised recommendations