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Friedel-crafts acylation of benzimidazolin-2-ones with aliphatic acid chlorides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The acylation of benzimidazolin-2-one and its 5,6-disubstituted derivatives with aliphatic acid chlorides in the presence of anhydrous aluminum chloride was studied. The corresponding 5(6)-acyl-, 5-R-6-acyl-, and 5,6-dimethyl-4-acylbenzimidaz-olin-2-ones, the structures of which were confirmed by the results of elementary analysis and IR, PMR, and mass spectroscopy, were obtained. The yields of the acylation products depend on the electronic effects of the substituents in the benzene ring of the benzimidazolin-2-one and on steric factors.

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Authors and Affiliations

  1. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent

    Ch. Sh. Kadyrov & S. S. Khalikov

Authors
  1. Ch. Sh. Kadyrov
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  2. S. S. Khalikov
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Translated from Khimiya Geterotsiklieheskikh Soedinenii, No. 6, pp. 808–811, June, 1984.

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Kadyrov, C.S., Khalikov, S.S. Friedel-crafts acylation of benzimidazolin-2-ones with aliphatic acid chlorides. Chem Heterocycl Compd 20, 658–661 (1984). https://doi.org/10.1007/BF00508678

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  • DOI: https://doi.org/10.1007/BF00508678

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