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Synthesis and properties of azoles and their derivatives. 34. Synthesis of 4-substituted 2-(3-indolyl)thiazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

4-Substituted 2-(3-indolyl)thiazoles were synthesized by condensation of indole-3-thiocarboxamide with halomethyl ketones. Reactions involving the nucleophilic substitution of the chlorine atom in 4-chloromethyl-2-(3-indolyl)thiazole were examined.

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Authors and Affiliations

  1. I. M. Gubkin Moscow Institute of the Petrochemical and Gas Industry, 117296, Moscow

    V. I. Kelarev & G. A. Shvekhgeimer

Authors
  1. V. I. Kelarev
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  2. G. A. Shvekhgeimer
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Additional information

See [1] for communication 33.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp, 761–764, June, 1984.

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Kelarev, V.I., Shvekhgeimer, G.A. Synthesis and properties of azoles and their derivatives. 34. Synthesis of 4-substituted 2-(3-indolyl)thiazoles. Chem Heterocycl Compd 20, 614–617 (1984). https://doi.org/10.1007/BF00508666

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  • DOI: https://doi.org/10.1007/BF00508666

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