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Synthesis of 2- and 4-azidopyrimidines containing an o-hydroxyphenyl group and their reaction with acetylene derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2- and 4-Azidopyrimidines that contain a phenyl and (or) o-hydroxyphenyl group were synthesized. Substituted 1-pyrimidyl-1,2,3-triazoles were obtained by the reaction of azidopyrimidines with acetylenes. Mixtures of isomeric 1,4- and 1,5-disubstituted triazoles, the ratios of which were determined from PMR-spectral data, were formed in the case of unsymmetrical acetylenes.

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Authors and Affiliations

  1. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, USSR

    V. P. Krivopalov, E. B. Nikolaenkova, V. F. Sedova & V. P. Mamaev

  2. Novosibirsk Branch, All-Union Scientific-Research Institute of Chemical Agents for the Protection of Plants, USSR

    V. P. Krivopalov, E. B. Nikolaenkova, V. F. Sedova & V. P. Mamaev

  3. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, 630090, Novosibirsk

    V. P. Krivopalov, E. B. Nikolaenkova, V. F. Sedova & V. P. Mamaev

Authors
  1. V. P. Krivopalov
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  2. E. B. Nikolaenkova
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  3. V. F. Sedova
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  4. V. P. Mamaev
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1222–1226, September, 1983.

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Krivopalov, V.P., Nikolaenkova, E.B., Sedova, V.F. et al. Synthesis of 2- and 4-azidopyrimidines containing an o-hydroxyphenyl group and their reaction with acetylene derivatives. Chem Heterocycl Compd 19, 977–981 (1983). https://doi.org/10.1007/BF00506884

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  • DOI: https://doi.org/10.1007/BF00506884

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