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Heterogeneous-catalytic fischer reaction. 13. Catalytic synthesis of 4-, 5-, 6-, and 7-methoxyindoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Methoxy-substituted acetaldehyde phenylhydrazones were cyclized in the vapor phase on a GIPKh-115 catalyst to give 4-, 5-, 6-, and 7-methoxyindoles. 5-Methoxyindole was obtained in 50% yield, 4- and 6-methoxyindoles were obtained in 85% yield, and 7-methoxyindole was obtained in 45% yield.

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Literature cited

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Authors and Affiliations

  1. D. I. Mendeleev Moscow Institute of Chemical Technology, 125047, Moscow

    N. N. Suvorov, V. N. Shkil'kova & N. Ya. Podkhalyuzina

Authors
  1. N. N. Suvorov
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  2. V. N. Shkil'kova
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  3. N. Ya. Podkhalyuzina
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Additional information

See [1] for Communication 12.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1054–1055, August, 1982.

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Suvorov, N.N., Shkil'kova, V.N. & Podkhalyuzina, N.Y. Heterogeneous-catalytic fischer reaction. 13. Catalytic synthesis of 4-, 5-, 6-, and 7-methoxyindoles. Chem Heterocycl Compd 18, 802–803 (1982). https://doi.org/10.1007/BF00506582

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  • DOI: https://doi.org/10.1007/BF00506582

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