Abstract
1,2,4-Triazolo[3,2-b]-1,3-thiazines were obtained by the reaction of 1,2,4,-triazole-3-thiones with an equimolar amount of 1-phenyl-2-cyanoacetylene in the presence of triethylamine or potassium hydroxide. It is shown that triazolethiones form N,S diadducts upon reaction with a twofold excess of cyanoacetylene. The nature of the heteroatom in the exo position of the heteroring affects the direction of addition to phenylcyanoacetylene. 2,4-Bis(1-phenyl-2-cyanovinylene)-1,2,4-triazol-3-one was synthesized.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1051–1053, August, 1982.
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Abramova, N.D., Trzhtsinskaya, B.V., Skvortsov, Y.M. et al. Synthesis of 1,2,4-triazolo[3,2-b]-1,3-thiazines. Chem Heterocycl Compd 18, 800–802 (1982). https://doi.org/10.1007/BF00506581
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DOI: https://doi.org/10.1007/BF00506581