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Synthesis and properties of 1-(5-halo-1-uracilyl)-β-D-glucofuranuronic acids

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

1-(5-Halo-1-uracilyl)-2, 5-di-O-acetyl-β-D-glucofuranurono-6,3-lactones were obtained by condensation of 2,4-bis(trimethylsilyl)-5-halouracils with 1,2,5-tri-O-acetyl-β-D-glucofuranurono;-6, 3-lactone. The chemical transformations of these compounds were studied. The structure of the glucuronides was proved by the IR, UV, circular dichroism, and NMR spectra.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1532–1537, November, 1981.

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Kilevitsa, M.K., Maurin'sh, Y.A., Paégle, R.A. et al. Synthesis and properties of 1-(5-halo-1-uracilyl)-β-D-glucofuranuronic acids. Chem Heterocycl Compd 17, 1120–1125 (1981). https://doi.org/10.1007/BF00506464

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  • DOI: https://doi.org/10.1007/BF00506464

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