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Alkylation and acylation of 2-aminopyrimidine N-oxides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Products of both O- and N-acylation are formed in the acylation of 2-aminopyrimidine N-oxides, whereas only O-alkylation products are formed by the action of alkylating agents. The reaction of 2-aminopyrimidine N-oxides with aldehydes gives only products of reaction at the amino group; the structures of the resulting compounds depend on the reactivity of the carbonyl component.

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Authors and Affiliations

  1. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, 630090, Novosibirsk

    V. F. Sedova, T. Yu. Mustafina & V. P. Mamaev

Authors
  1. V. F. Sedova
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  2. T. Yu. Mustafina
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  3. V. P. Mamaev
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1515–1522, November, 1981.

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Sedova, V.F., Mustafina, T.Y. & Mamaev, V.P. Alkylation and acylation of 2-aminopyrimidine N-oxides. Chem Heterocycl Compd 17, 1105–1112 (1981). https://doi.org/10.1007/BF00506462

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  • DOI: https://doi.org/10.1007/BF00506462

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