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Unusual fischer reaction in the 1-aminobenzimidazole series. Synthesis of pyrido [1,2-a]benzimidazole derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of N-aminobenzimidazoles with ketones under the conditions of the Fischer reaction, as a result of which derivatives of 1,3-disubstituted pyrido-[1,2-a]benzimidazoles are unexpectedly formed, was investigated. The structure of the latter was established on the basis of data from IR, PMR, and mass spectroscopy, as well as by an independent method based on 2-cyanomethylbenzimidazole and ß-diketones.

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Authors and Affiliations

  1. Scientific-Research Institute of Physical and Organic Chemistry, Rostov State University, 344006, Rostov-on-Don

    V. V. Kuz'menko, V. N. Komissarov & A. M. Simonov

Authors
  1. V. V. Kuz'menko
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  2. V. N. Komissarov
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  3. A. M. Simonov
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Additional information

Translated from Khimiya Geterotsikilicheskikh Soedinenii, No. 11, pp. 1497–1502, November, 1981.

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Kuz'menko, V.V., Komissarov, V.N. & Simonov, A.M. Unusual fischer reaction in the 1-aminobenzimidazole series. Synthesis of pyrido [1,2-a]benzimidazole derivatives. Chem Heterocycl Compd 17, 1090–1095 (1981). https://doi.org/10.1007/BF00506458

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  • DOI: https://doi.org/10.1007/BF00506458

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