Abstract
In the reaction of N-[2-(5-bromouracil-1-yl)ethyl]alkylamines with alkylamines at 40 °C kine-substitution takes place with the formation of N-[2-(6-alkylamino-uracil-1-yl)ethyl]alkylamines.
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R. A. Paégle, I. Zh. Lulle, V. É. Krishane, I. B. Mazheika, É. É. Liepin'sh, and M. Yu. Lidak, Khim. Geterotsikl. Soedin., No. 4, 538 (1980).
I. Zh. Lulle, R. A. Paégle, M. Yu. Lidak, and I. B. Mazheika, Khim. Geterotsikl. Soedin., No. 4, 535 (1982).
A. Matsuda, H. Inoue, and T. Ueda, Chem. Pharm. Bull., 26, 2340 (1978).
H. Inoue and T. Ueda, Chem. Pharm. Bull., 26, 2657 (1978).
S. Senda, K. Hirota, and T. Asao, J. Org. Chem., 40, 353 (1975).
T. K. Bradshaw and D. W. Hutchinson, Chem. Soc. Rev., 6, 43 (1977).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1260–1261, September, 1984.
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Lulle, I.Z., Paégle, R.A. & Lidak, M.Y. Kine-substitution in the N-[ω-(5-bromouracil-1-yl)alkyl]alkylamine series. Chem Heterocycl Compd 20, 1033–1035 (1984). https://doi.org/10.1007/BF00506403
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DOI: https://doi.org/10.1007/BF00506403