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Synthesis and properties of 9-thia-1,4-diazaspiro[5.5]undecanes

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

4-Bromo-4-formyltetrahydrothiopyrans, which were used to develop a method for the synthesis of 8,8-dialkyl-9-thia-1,4-diazaspiro[5.5]undecanes, were synthesized from 4-formyltetrahydrothiopyrans. Alkylation of these products with ethyl bromoacetate and ethyl acrylate gave, respectively, their di- and monosubstituted derivatives.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 920–922, July, 1983.

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Kuroyan, R.A., Sarkisyan, V.V. & Vartanyan, S.A. Synthesis and properties of 9-thia-1,4-diazaspiro[5.5]undecanes. Chem Heterocycl Compd 19, 737–740 (1983). https://doi.org/10.1007/BF00506097

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  • DOI: https://doi.org/10.1007/BF00506097

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