Abstract
The interaction of methyl 3-oxo-4-(phenylthio)butyrate with formaldehyde and ammonium acetate yielded 5-methoxycarbonyl-6-oxo-7-phenylthio-1,3-diazaadamantane, which, on being heated with skeletal nickel in isopropanol was converted into 6-hydroxy-5-methoxycarbonyl-1,3-diazaadamantane. The structures of the compounds have been confirmed by IR and PMR spectroscopy.
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For Communication 2, see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 661–663, May, 1985.
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Kuznetsov, A.I., Boiko, I.P., Sokolova, E.B. et al. Heteroadamantanes and their derivatives. 3. The synthesis of 6-hydroxy-5-methoxycarbonyl-1,3-diazaadamantane. Chem Heterocycl Compd 21, 557–559 (1985). https://doi.org/10.1007/BF00506073
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DOI: https://doi.org/10.1007/BF00506073