Abstract
Depending on the reaction conditions, the bromination of 3-acyl-5-hydroxybenzofurans leads to 4-bromo and 4,6-dibromo derivatives, whereas chlorination leads to replacement of the hydrogen atom in the 4 position. As in the nitration of 3-acyl-5-hydroxybenzofurans with a nitrating mixture, 3-acyl-4,6-dinitro-5-hydroxybenzofurans are formed in the nitration of 3-acyl-5-hydroxybenzofurans with nitric acid.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1314–1317, October, 1983.
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Grinev, A.N., Mukhanova, T.I., Zinov'eva, R.A. et al. Halogenation and nitration of 3-acyl-5-hydroxy(acetoxy)benzofurans. Chem Heterocycl Compd 19, 1044–1047 (1983). https://doi.org/10.1007/BF00505747
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DOI: https://doi.org/10.1007/BF00505747