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Synthesis of some 4-thiazolidone derivatives from 4-(cyclo-3-alkenyl)thiosemicarbazones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 4-(cyclo-3-pentenyl)- and 4-(cyclo-3-hexenyl) thiosemicarbazones with chloroacetic acid gave 2-hydrazono derivatives of 3-cyclo-pentenyl (cyclohexenyl) thioazolid-4-one, the condensation of which with aromatic aldehydes gave 5-benzylidene derivatives. Representatives of 4-thiazolidone with a carboxy group in the 5 position were synthesized by condensation of the same thiosemicarbazones with maleic anhydride. Some of the substances obtained have bactericidal activity.

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Authors and Affiliations

  1. Uzhgorod State University, 294005, Uzhgorod

    I. V. Smolanka, N. P. Man'o & T. A. Krasnitskaya

Authors
  1. I. V. Smolanka
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  2. N. P. Man'o
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  3. T. A. Krasnitskaya
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 627–628, May, 1981.

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Smolanka, I.V., Man'o, N.P. & Krasnitskaya, T.A. Synthesis of some 4-thiazolidone derivatives from 4-(cyclo-3-alkenyl)thiosemicarbazones. Chem Heterocycl Compd 17, 457–458 (1981). https://doi.org/10.1007/BF00505687

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  • DOI: https://doi.org/10.1007/BF00505687

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