Abstract
It has previously been observed that the carbamide residue in 2-phenacyl-3-ureido- and 2-cyanomethylpyridine is readily cleaved on cyclization to pyridothiazines [1–4]. It was of interest to establish whether a similar process occurs when the carbonyl component is an α-halo- or unsaturated acid. If this were the case, this reaction could be used to obtain 6-oxopyrido[2,3-b][1,4]thiazines.
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For communication 42, see [6].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 214–218, February, 1985.
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Traven', N.I., Safonova, T.S. Nitrogen-, oxygen-, and sulfur-containing heterocycles. 43. Synthesis and properties of 6-oxo-5H-pyrido[2,3-b][1,4]thiazines. Chem Heterocycl Compd 21, 176–180 (1985). https://doi.org/10.1007/BF00504204
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DOI: https://doi.org/10.1007/BF00504204