Chemistry of Heterocyclic Compounds

, Volume 16, Issue 11, pp 1112–1114 | Cite as

Transformations of anthra[1,9-cd]isoxazol-6-ones in hydrohalic acids

  • L. M. Gornostaev
  • V. T. Sakilidi


4-Halo-1-aminoanthraquinones are formed when anthra [1,9-cd]isoxazol-6-ones are refluxed in hydrohalic acids. The 3 position undergoes halogenation when 5-substituted isoxazoles are used. The process takes place via a one-proton mechanism with the participation of halide ion in the rate-determining step, possibly with the intermediate formation of N-haloaminoanthraquinones.


Organic Chemistry Halide Halogenation Intermediate Formation Isoxazoles 
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Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • L. M. Gornostaev
    • 1
  • V. T. Sakilidi
    • 1
  1. 1.Krasnoyarsk State Pedagogical InstituteKrasnoyarsk

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